Some articles you should read to know more about Saas and Cloud Computing.
http://en.wikipedia.org/wiki/Cloud_computing
In this article I found some real good tips, about the cloud products...
http://blog.softwareinsider.org/2010/08/10/tuesdays-tip-10-saascloud-strategies-for-legacy-apps-environments/
If you want to know more about cloud computing and its differences with Saas (software as a service ) read this
http://www.mindtouch.com/blog/2008/05/28/differences-between-saas-and-cloud-software/
When we talk of security, we need to look a step beyond the regular virus checks etc.
McAfee has a security suite....
http://www.internetnews.com/security/article.php/3890456/McAfee-Rolls-Out-SaaS-Cloud-Security-Suite.htm
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Regards
Vijayashankar